Human IL-17A

Interleukin-17A (IL-17A) is a cytokine encoded by the IL17A gene, playing a critical role in both innate and adaptive immune responses. It regulates NF-kappaB and MAPK pathways, stimulating the production of pro-inflammatory cytokines like IL-6 and COX-2, and enhancing nitric oxide (NO) production. IL-17A signals through a receptor complex composed of IL17RA and IL17RC, leading to robust immune inflammation and driving neutrophil activation and recruitment at infection sites. 
License Type
Product number: SW10067.1

TU-1

hERP29 Proximal Promoter, a Synthetic Splice, and a portion of the hACTB gene.

A portion of the hUCP2 Proximal Promoter, a Synthetic Splice, and a terminal portion of the hS100A11 gene.

A portion of the hEIF-4A1 Proximal Promoter, a Synthetic Splice, and a terminal portion of the hADAM9 gene.

A portion of the hPCNA Proximal Promoter, a Synthetic Splice, and a terminal portion of the hCOL5A1 gene.

A portion of the Murine Cytohesin-1 Proximal Promoter, a Synthetic Splice, and a terminal portion of the hACTN1 gene.

A portion of the Mus E2A Proximal Promoter, a Synthetic Splice, and a terminal portion of the hKDELR3 gene.

A portion of the hPNP Proximal Promoter, a Synthetic Splice, and a terminal portion of the hANPEP gene. 

A portion of the bMHC Proximal Promoter, a Synthetic Splice, and a terminal portion of the hCD58 gene

*NOTE: bMHC info (USPTO-US005441889A)

hERP29 Proximal Promoter, a Synthetic Splice, and a portion of the hACTB gene.

A portion of the hUCP2 Proximal Promoter, a Synthetic Splice, and a terminal portion of the hS100A11 gene.

A portion of the hEIF-4A1 Proximal Promoter, a Synthetic Splice, and a terminal portion of the hADAM9 gene.

A portion of the hPCNA Proximal Promoter, a Synthetic Splice, and a terminal portion of the hCOL5A1 gene.

A portion of the Murine Cytohesin-1 Proximal Promoter, a Synthetic Splice, and a terminal portion of the hACTN1 gene.

A portion of the Mus E2A Proximal Promoter, a Synthetic Splice, and a terminal portion of the hKDELR3 gene.

A portion of the hPNP Proximal Promoter, a Synthetic Splice, and a terminal portion of the hANPEP gene. 

A portion of the bMHC Proximal Promoter, a Synthetic Splice, and a terminal portion of the hCD58 gene

*NOTE: bMHC info (USPTO-US005441889A)