TU-14
Patent Pending
OspreyBio's Transcription Units (TU) are built from a series of natural and/or synthetic modules that are mutated to be compliant with the Bird of Prey DNA Design and Assembly System.
Transcription Unit architecture is defined by a 5' Transcription Regulatory Module (R) and a 3' Transcription Processing Module (P).
The Transcription Regulatory Module (R) frequently includes DNA-encoded Promoter, Enhancer, Repressor Elements and/or chromatin modulators. Additionally, the "R" Module can include splicing elements and/or 5' untranslated regions (5' UTR). The Transcription Processing Module (P) frequently includes 3' Untranslated Regions (3'UTR), splicing elements, polyA signal(s), strong transcription terminators, and/or chromatin modulators.
- Ready-to-use plasmid after just one elution (~1 hour)
- Safe Long Term Storage: Can be stored flat at ambient temperature without the need for uninterrupted electricity supply (as in freezer storage) or the need for isolation from harmful agents (such as metal ions)
TU-14
The “R” Domain contains elements derived from the bMHC Proximal Promoter along with a unique Synthetic Splice Unit. The “P” Domain contains elements derived from the hNT5E gene. |
The “R” Domain contains elements derived from the JET PROMOTER along with a unique Synthetic Splice Unit. The “P” Domain contains elements derived from the hCD81 gene. |
The “R” Domain contains elements derived from the hUBB Proximal Promoter along with a unique Synthetic Splice Unit. The “P” Domain contains elements derived from the hCD151 gene. |
The “R” Domain contains elements derived from the hHLA-C Proximal Promoter. The “P” Domain contains elements derived from the hACTN1 gene. |
The “R” Domain contains elements derived from the hABCA1 Proximal Promoter. The “P” Domain contains elements derived from the hCAV1 gene. |
The “R” Domain contains elements derived from the hSLC25A5 Proximal Promoter. The “P” Domain contains elements derived from the hTAGLN1 gene. |
The “R” Domain contains elements derived from the hCD81 Proximal Promoter. The “P” Domain contains elements derived from the hANAX5 gene. |
The “R” Domain contains elements derived from the EF1a Proximal Promoter. The “P” Domain contains elements derived from the bGH gene. |
The “R” Domain contains elements derived from the bMHC Proximal Promoter along with a unique Synthetic Splice Unit. The “P” Domain contains elements derived from the hNT5E gene. |
The “R” Domain contains elements derived from the JET PROMOTER along with a unique Synthetic Splice Unit. The “P” Domain contains elements derived from the hCD81 gene. |
The “R” Domain contains elements derived from the hUBB Proximal Promoter along with a unique Synthetic Splice Unit. The “P” Domain contains elements derived from the hCD151 gene. |
The “R” Domain contains elements derived from the hHLA-C Proximal Promoter. The “P” Domain contains elements derived from the hACTN1 gene. |
The “R” Domain contains elements derived from the hABCA1 Proximal Promoter. The “P” Domain contains elements derived from the hCAV1 gene. |
The “R” Domain contains elements derived from the hSLC25A5 Proximal Promoter. The “P” Domain contains elements derived from the hTAGLN1 gene. |
The “R” Domain contains elements derived from the hCD81 Proximal Promoter. The “P” Domain contains elements derived from the hANAX5 gene. |
The “R” Domain contains elements derived from the EF1a Proximal Promoter. The “P” Domain contains elements derived from the bGH gene. |