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Interleukin-17A (IL-17A) is a cytokine encoded by the IL17A gene, playing a critical role in both innate and adaptive immune responses. It regulates NF-kappaB and MAPK pathways, stimulating the production of pro-inflammatory cytokines like IL-6 and COX-2, and enhancing nitric oxide (NO) production. IL-17A signals through a receptor complex composed of IL17RA and IL17RC, leading to robust immune inflammation and driving neutrophil activation and recruitment at infection sites.