$65.00 - $125.00
A cytokine with anti-inflammatory and proangiogenic properties that promotes an anti-inflammatory immune response by inducing T-helper 2 polarization, characterized by the down-regulation of IFN-gamma and up-regulation of IL-4 and IL-5. Produced by osteocytes, IL-19 also stimulates granulopoiesis and neutrophil formation. It exerts its effects through a receptor complex formed by IL20RA and IL20RB, activating the JAK-STAT signaling pathway, particularly STAT3.